Clinical and Laboratory Characteristics of Infectious Mononucleosis Caused by Epstein-Barr Virus and Cytomegalovirus

Abstract

Infectious mononucleosis is a widespread infectious disease worldwide, most often caused by the γ-herpetic Epstein-Barr virus (EBV), affecting 80-90% of the population. Currently, there has been an increase in the incidence rate of infectious mononucleosis among children. To some extent, this is due to the insufficient improvement of diagnostics. If we analyze the official data, in 2000-2019, the statistics of EBV infection in Novokuznetsk increased by 27 times: from 0.9 per 100 thousand population in 2000 to 24.7 in 2008. This is primarily due to the high incidence rate, for example, in Uzbekistan, it occurs in the ratio of 7.5:100,000, and among children, the highest ratio is 34:100,000.