STATUS OF RENAL HEMODYNAMICS IN CHILDREN AND ADOLESCENTS WITH OBESITY

Abstract

The study involved 35 children aged 7 to 18 years (mean age of children 12.14±0.18 years), with exogenous constitutional obesity. The control group included 20 practically healthy children with normal body weight. In this study, a clear relationship was obtained between the degree of obesity and the severity of carbohydrate metabolism disorders and dyslipidemia in children and adolescents, which was expressed in an increase in the level of cholesterol, triglycerides, LDL and in a decrease in HDL, an increase in immunoreactive insulin and an increase in the IR HOMA R. in children with high microalbuminuria. It was revealed that in children with obesity and microalbuminuria, violations of renal hemodynamics at the level of interlobar and arcuate renal arteries are determined. A statistically significant decrease in Vmin at the level of large renal vessels allows us to consider these changes as a marker of early renal hemodynamic disorders.