Factors of Control and Monitoring of Recovery after Illness

Abstract

The revolutionary achievements of molecular genetics in recent decades have radically changed the understanding of the true nature of congenital hearing loss and determined the revision of the ratio (share) of causes in the etiological structure. Changes in the genotype are the cause of hearing impairment in 70% of children with congenital and pre-speech hearing loss, and in 70-85% of cases these are non-syndromic forms. More than 100 genes encode membrane, regulatory and structural proteins of the inner ear. Mutations in them lead to disruption of the organ of Corti, and, accordingly, to peripheral hearing loss.