Types and Diagnosis of the Sex Chromosome Linked Disease - Hemophilia

Abstract

Hemophilia is a hereditary disease that can cause serious complications due to impaired blood clotting. In most cases, the cause of the disease in boys in a family is the recessive type linked to the sex X-chromosome, and in most cases, mothers retain the carrier gene and pass it on to their sons. However, cases of girls being born with hemophilia have also been reported. In such cases, girl are affected when both parents are affected, meaning that the patient's father is affected and the mother is a carrier of the disease. Hemophilia is also called the disease of kings, because this pathology was identified among representatives of the English monarchy.