Pathomorphology of Immunohistochemical Aspects of Vascular Endothelial Growth Factor in Pulmonary Artery Thromboembolism Developed After Surgical Intervention

Abstract

In thromboembolic syndromes of various etiologies, immunohistochemical studies of pulmonary vessels are primarily aimed at examining damage to the inner surface of the vessels and the processes of thrombogenesis within the vascular wall using various immunohistochemical markers. These studies are essential for assessing the morphological state of endothelial cells in the vascular intima and identifying molecular substrates responsible for pulmonary artery damage in thromboembolism. In particular, the detection of factors enhancing blood coagulation in the vascular endothelium using the CD31 marker represents an important step in evaluating the expression of the corresponding genes.