Clinical and Diagnostic Characteristics of Bronchopulmonary Pathology in Children Taking into Account the Microbiota of the Lungs and Intestines and the Effectiveness of Probiotic Correction

Abstract

The article presents the results of a clinical and microbiological assessment of bronchopulmonary pathology in children, taking into account the state of the microbiota of the respiratory tract and intestines, and also evaluates the effectiveness of combined probiotic therapy. A total of 140 children aged from 3 months to 14 years were examined. It was found that the severity of dysbiotic changes of the intestinal microflora correlates with the severity of bronchopulmonary pathology (r = 0.74; p < 0.001). The use of a combined scheme of probiotic therapy with Saccharomyces boulardii and Bacillus cereus contributed to the normalization of microbiocenosis in 78.2% of patients and to a threefold reduction in the frequency of disease recurrences.