Psychological Impacts and Treatment Strategies in Patients With Liver Cirrhosis

Abstract

Liver cirrhosis, the final stage of chronic liver disease, poses significant psychological challenges alongside its physical manifestations. This study explores the psychological impacts of liver cirrhosis, focusing on the prevalence of depression, anxiety, and cognitive impairments, and evaluates the effectiveness of current treatment strategies. Despite extensive research on physical symptoms, the psychological aspects of liver cirrhosis remain underexplored, revealing a critical knowledge gap in integrated care approaches. Employing a mixed-methods approach, this study integrates quantitative assessments using the Hospital Anxiety and Depression Scale (HADS), Beck Depression Inventory (BDI), and Mini-Mental State Examination (MMSE), with qualitative insights from interviews with hepatologists, psychologists, and psychiatrists. Findings indicate high prevalence rates of anxiety (65%), depression (58%), and cognitive impairments (45%) among patients. Qualitative data highlight that psychological distress exacerbates physical symptoms and complicates disease management, emphasizing the need for comprehensive mental health care. The study's implications underscore the necessity for integrated care models that combine psychological and physical treatments to improve patient outcomes. Future research should focus on longitudinal studies to assess the long-term psychological effects and the efficacy of integrated care models, and develop robust theoretical frameworks for psychological interventions in liver cirrhosis management. This comprehensive approach aims to enhance patient care and address the identified gaps in current treatment strategies.